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Dissection of the Adenoviral VA RNA(I) Central Domain Structure Reveals Minimum Requirements for RNA-mediated Inhibition of PKR
Virus-associated RNA I (VA RNA(I)) is a short (∼160-nucleotide) non-coding RNA transcript employed by adenoviruses to subvert the innate immune system protein double-stranded RNA-activated protein kinase (PKR). The central domain of VA RNA(I) is proposed to contain a complex tertiary structure that...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132820/ https://ncbi.nlm.nih.gov/pubmed/24970889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550046 |
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