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Platelet-derived Growth Factor Primes Cancer-associated Fibroblasts for Apoptosis
Desmoplastic malignancies such as cholangiocarcinoma (CCA) are characterized by a dense stroma containing an abundance of myofibroblasts termed cancer-associated fibroblasts (CAF). The CAF phenotype represents an “activated state” in which cells are primed for cell death triggered by BH3 mimetics. A...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132787/ https://ncbi.nlm.nih.gov/pubmed/24973208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563064 |
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