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In vitro selection of DNA-cleaving deoxyribozyme with site-specific thymidine excision activity
Single-nucleotide polymorphisms, either inherited or due to spontaneous DNA damage, are associated with numerous diseases. Developing tools for site-specific nucleotide modification may one day provide a way to alter disease polymorphisms. Here, we describe the in vitro selection and characterizatio...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132718/ https://ncbi.nlm.nih.gov/pubmed/25030901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku592 |
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