Intracellular selection of trans-cleaving hammerhead ribozymes

Hammerhead ribozyme is the smallest and best characterized catalytic RNA-cleaving ribozyme. It has been reported as potential therapeutic tools to manipulate the expression of target genes. However, most of naturally occurring hammerhead ribozymes process self-cleavage rather than cleave substrate R...

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Pubblicato in:Nucleic Acids Res
Autori principali: Huang, Xin, Zhao, Yongyun, Pu, Qinlin, Liu, Getong, Peng, Yan, Wang, Fei, Chen, Gangyi, Sun, Meiling, Du, Feng, Dong, Juan, Cui, Xin, Tang, Zhuo, Mo, Xianming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Nucleic Acid Enzymes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412130/
https://ncbi.nlm.nih.gov/pubmed/30649474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz018
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