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Intracellular Selection of Theophylline-Sensitive Hammerhead Aptazyme

Hammerhead ribozyme-based aptazyme (HHAz), inheriting the advantages of small size and high efficiency from the RNA-cleaving ribozyme and the specific recognition ability of aptamers to specific targets, exhibits the huge potential to be a transgene expression regulator. Herein, we report a selectio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Pu, Qinlin, Zhou, Shan, Huang, Xin, Yuan, Yi, Du, Feng, Dong, Juan, Chen, Gangyi, Cui, Xin, Tang, Zhuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118274/
https://ncbi.nlm.nih.gov/pubmed/32244167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.03.001
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