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MYC is essential for the formation and maintenance of germinal centers
Germinal centers (GC) are sites of intense B cell proliferation, central for T cell dependent antibody responses. However, the role of MYC, a key cell cycle regulator, in this process has been questioned. Here, we identified MYC positive B cell subpopulations in immature and mature GCs, and show thr...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132664/ https://ncbi.nlm.nih.gov/pubmed/23001146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2418 |
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