Synergy between PI3K Signaling and MYC in Burkitt Lymphomagenesis

In Burkitt lymphoma (BL), a germinal center B-cell-derived tumor, the pro-apoptotic properties of c-MYC must be counterbalanced. Predicting that survival signals would be delivered by phosphoinositide-3-kinase (PI3K), a major survival determinant in mature B cells, we indeed found that combining con...

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Hlavní autoři: Sander, Sandrine, Calado, Dinis P., Srinivasan, Lakshmi, Köchert, Karl, Zhang, Baochun, Rosolowski, Maciej, Rodig, Scott J., Holzmann, Karlheinz, Stilgenbauer, Stephan, Siebert, Reiner, Bullinger, Lars, Rajewsky, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432451/
https://ncbi.nlm.nih.gov/pubmed/22897848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.06.012
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