MYC is essential for the formation and maintenance of germinal centers

Germinal centers (GC) are sites of intense B cell proliferation, central for T cell dependent antibody responses. However, the role of MYC, a key cell cycle regulator, in this process has been questioned. Here, we identified MYC positive B cell subpopulations in immature and mature GCs, and show thr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Calado, Dinis Pedro, Sasaki, Yoshiteru, Godinho, Susana A., Pellerin, Alex, Köchert, Karl, Sleckman, Barry P., de Alborán, Ignacio Moreno, Janz, Martin, Rodig, Scott, Rajewsky, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132664/
https://ncbi.nlm.nih.gov/pubmed/23001146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2418
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge