Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cells

The intestinal brush border Na(+)/H(+) exchanger NHE3 is tightly regulated through changes in its endocytosis and exocytosis. Myosin VI, a minus-end-directed actin motor, has been implicated in endocytosis at the inter-microvillar cleft and during vesicle remodeling in the terminal web. Here, we ask...

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Autores principales: Chen, Tiane, Hubbard, Ann, Murtazina, Rakhilya, Price, Jennifer, Yang, Jianbo, Cha, Boyoung, Sarker, Rafiquel, Donowitz, Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132392/
https://ncbi.nlm.nih.gov/pubmed/24928903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.149930
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