Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein.

The adenovirus E1A proteins differentially regulate AP-1-responsive genes. Collagenase and stromelysin are repressed by E1A, whereas the expression of c-jun is elevated. Inhibition of collagenase has been found to be exerted through the consensus AP-1 binding site TGAGTCA. Here we show that the dist...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: van Dam, H, Duyndam, M, Rottier, R, Bosch, A, de Vries-Smits, L, Herrlich, P, Zantema, A, Angel, P, van der Eb, A J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1993
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413231/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8382609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05680.x
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