Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein.

The adenovirus E1A proteins differentially regulate AP-1-responsive genes. Collagenase and stromelysin are repressed by E1A, whereas the expression of c-jun is elevated. Inhibition of collagenase has been found to be exerted through the consensus AP-1 binding site TGAGTCA. Here we show that the dist...

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Main Authors: van Dam, H, Duyndam, M, Rottier, R, Bosch, A, de Vries-Smits, L, Herrlich, P, Zantema, A, Angel, P, van der Eb, A J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC413231/
https://ncbi.nlm.nih.gov/pubmed/8382609
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