cJun-assisted loading of RelA DNA-binding promotes synergistic lung epithelial antimicrobial responses

Summary: Lower respiratory tract infections remain a leading cause of death worldwide, highlighting the need for host-directed therapies. We previously identified an inhaled immunostimulatory combination of Pam2CSK4 (Pam2) and CpG oligodeoxynucleotide ODN M362 (ODN) that synergistically protects aga...

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Auteurs principaux:	Jezreel Pantaleón García, Keerthi Bhoda, Madeleine Burch-Eapen, Raquel Alonso Becerra, Paris Rodríguez Carstens, Daniela Covarrubias López, Jania Foncerrada Lizaola, Vikram V. Kulkarni, Jose Martinez, III, Yongxing Wang, Scott E. Evans
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2026-05-01
Collection:	iScience
Sujets:	respiratory medicine microbiology
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2589004226009673
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