The Role of Nibrin in Doxorubicin-Induced Apoptosis and Cell Senescence in Nijmegen Breakage Syndrome Patients Lymphocytes

Nibrin plays an important role in the DNA damage response (DDR) and DNA repair. DDR is a crucial signaling pathway in apoptosis and senescence. To verify whether truncated nibrin (p70), causing Nijmegen Breakage Syndrome (NBS), is involved in DDR and cell fate upon DNA damage, we used two (S4 and S3...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Alster, Olga, Bielak-Zmijewska, Anna, Mosieniak, Grazyna, Moreno-Villanueva, Maria, Dudka-Ruszkowska, Wioleta, Wojtala, Aleksandra, Kusio-Kobiałka, Monika, Korwek, Zbigniew, Burkle, Alexander, Piwocka, Katarzyna, Siwicki, Jan K., Sikora, Ewa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132076/
https://ncbi.nlm.nih.gov/pubmed/25119968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104964
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items