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Feasibility Study of Intra-patient Sorafenib Dose-Escalation or Re-Escalation in Patients with Previously Treated Advanced Solid Tumors
PURPOSE: To determine if intra-patient dose escalation of the multi-targeted kinase inhibitor sorafenib is feasible in patients with advanced pretreated solid malignancies. METHODS: An intra-patient dose escalation scheme starting at 400 mg BID was employed in this prospective trial. Doses were esca...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131984/ https://ncbi.nlm.nih.gov/pubmed/22015991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-011-9761-y |
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