Escalating weekly doses of cetuximab and correlation with skin toxicity: A phase I study

BACKGROUND: Cetuximab is a chimeric monoclonal antibody targeting the epidermal growth factor receptor (EGFR). The recommended dosage is an initial load of 400 mg/m(2) intravenously (IV) followed by a weekly maintenance dose of 250 mg/m(2). It has been reported retrospectively that cetuximab efficac...

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Publicado no:Invest New Drugs
Main Authors: Ho, Cheryl, Sangha, Randeep, Beckett, Laurel, Tanaka, Michael, Lau, Derick H., Eisen, Daniel B., Burich, Rachel A., Luciw, Paul, Khan, Imran, Mack, Philip C., Gandara, David R., Davies, Angela M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559347/
https://ncbi.nlm.nih.gov/pubmed/20148348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9396-4
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