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Mechanistic Insights into the Allosteric Modulation of Opioid Receptors by Sodium Ions
[Image: see text] The idea of sodium ions altering G-protein-coupled receptor (GPCR) ligand binding and signaling was first suggested for opioid receptors (ORs) in the 1970s and subsequently extended to other GPCRs. Recently published ultra-high-resolution crystal structures of GPCRs, including that...
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| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131901/ https://ncbi.nlm.nih.gov/pubmed/25073009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5006915 |
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