Autoantibody-mediated complement C3a receptor activation contributes to the pathogenesis of preeclampsia

Preeclampsia (PE) is a prevalent life-threatening hypertensive disorder of pregnancy associated with increased complement activation. However, the causative factors and pathogenic role of increased complement activation in PE are largely unidentified. Here we report that a circulating maternal autoa...

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Autors principals: Wang, Wei, Irani, Roxanna A., Zhang, Yujin, Ramin, Susan M., Blackwell, Sean C., Tao, Lijian, Kellems, Rodney E., Xia, Yang
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131740/
https://ncbi.nlm.nih.gov/pubmed/22868393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.191817
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