Angiotensin receptor agonistic autoantibody-mediated TNF-α induction contributes to increased soluble endoglin production in preeclampsia

BACKGROUND: Preeclampsia (PE) is a prevalent life-threatening hypertensive disorder of pregnancy. The circulating antiangiogenic factor, soluble endoglin (sEng), is elevated in the blood circulation of women with PE and contributes to disease pathology. However, the underlying mechanisms responsible...

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Main Authors: Zhou, Cissy Chenyi, Irani, Roxanna A., Zhang, Yujin, Blackwell, Sean, Mi, Tiejuan, Wen, Jiaming, Shelat, Harnath, Geng, Yong-Jian, Ramin, Susan M., Kellems, Rodney E., Xia, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844327/
https://ncbi.nlm.nih.gov/pubmed/20065159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.902890
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