Angiotensin receptor agonistic autoantibody-mediated TNF-α induction contributes to increased soluble endoglin production in preeclampsia

BACKGROUND: Preeclampsia (PE) is a prevalent life-threatening hypertensive disorder of pregnancy. The circulating antiangiogenic factor, soluble endoglin (sEng), is elevated in the blood circulation of women with PE and contributes to disease pathology. However, the underlying mechanisms responsible...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhou, Cissy Chenyi, Irani, Roxanna A., Zhang, Yujin, Blackwell, Sean, Mi, Tiejuan, Wen, Jiaming, Shelat, Harnath, Geng, Yong-Jian, Ramin, Susan M., Kellems, Rodney E., Xia, Yang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844327/
https://ncbi.nlm.nih.gov/pubmed/20065159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.902890
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