Angiotensin receptor agonistic autoantibody-mediated sFlt-1 induction contributes to impaired adrenal vasculature and decreased aldosterone production in preeclampsia

Preeclampsia (PE) is a life-threatening hypertensive disorder of pregnancy associated with decreased circulating aldosterone levels. However, the molecular mechanisms underlying aldosterone reduction in PE remain unidentified. Here we demonstrate that reduced circulating aldosterone levels in the pr...

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Hauptverfasser: Siddiqui, Athar H., Irani, Roxanna A., Zhang, Weiru, Wang, Wei, Blackwell, Sean C., Kellems, Rodney E., Xia, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131732/
https://ncbi.nlm.nih.gov/pubmed/23283357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00157
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