Angiotensin receptor agonistic autoantibody-mediated sFlt-1 induction contributes to impaired adrenal vasculature and decreased aldosterone production in preeclampsia

Preeclampsia (PE) is a life-threatening hypertensive disorder of pregnancy associated with decreased circulating aldosterone levels. However, the molecular mechanisms underlying aldosterone reduction in PE remain unidentified. Here we demonstrate that reduced circulating aldosterone levels in the pr...

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Main Authors: Siddiqui, Athar H., Irani, Roxanna A., Zhang, Weiru, Wang, Wei, Blackwell, Sean C., Kellems, Rodney E., Xia, Yang
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131732/
https://ncbi.nlm.nih.gov/pubmed/23283357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00157
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