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Angiotensin receptor agonistic autoantibody-mediated sFlt-1 induction contributes to impaired adrenal vasculature and decreased aldosterone production in preeclampsia

Preeclampsia (PE) is a life-threatening hypertensive disorder of pregnancy associated with decreased circulating aldosterone levels. However, the molecular mechanisms underlying aldosterone reduction in PE remain unidentified. Here we demonstrate that reduced circulating aldosterone levels in the pr...

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Huvudupphovsmän: Siddiqui, Athar H., Irani, Roxanna A., Zhang, Weiru, Wang, Wei, Blackwell, Sean C., Kellems, Rodney E., Xia, Yang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131732/
https://ncbi.nlm.nih.gov/pubmed/23283357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00157
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