Mechanistic Target of Rapamycin Complex 2 Protects the Heart From Ischemic Damage

BACKGROUND: The mechanistic target of rapamycin (mTOR) comprises 2 structurally distinct multiprotein complexes, mTOR complexes 1 and 2 (mTORC1 and mTORC2). Deregulation of mTOR signaling occurs during and contributes to the severity of myocardial damage from ischemic heart disease. However, the rel...

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Hauptverfasser: Völkers, Mirko, Konstandin, Mathias H., Doroudgar, Shirin, Toko, Haruhiro, Quijada, Pearl, Din, Shabana, Joyo, Anya, Ornelas, Luis, Samse, Kaitleen, Thuerauf, Donna J., Gude, Natalie, Glembotski, Christopher C., Sussman, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131547/
https://ncbi.nlm.nih.gov/pubmed/24008870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.003638
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