Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity.
The 5' flanking region of the human alpha-globin gene is highly G + C rich and contains multiple copies of the consensus sequence for the Sp1 binding site. We investigated the role of this G + C-rich region in augmenting alpha-globin promoter activity in the presence of the far-upstream alpha-globin...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7638173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7237 |
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