E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition

BACKGROUND: E-cadherin is an adherens junction protein that forms homophilic intercellular contacts in epithelial cells while also interacting with the intracellular cytoskeletal networks. It has roles including establishment and maintenance of cell polarity, differentiation, migration and signallin...

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Main Authors: Chen, Augustine, Beetham, Henry, Black, Michael A, Priya, Rashmi, Telford, Bryony J, Guest, Joanne, Wiggins, George A R, Godwin, Tanis D, Yap, Alpha S, Guilford, Parry J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131020/
https://ncbi.nlm.nih.gov/pubmed/25079037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-552
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