Protein synthesis in rabbit reticulocytes: mechanism of protein synthesis inhibition by heme-regulated inhibitor.

Partially purified Met-tRNAf binding factor, eIF-2, was phosphorylated by using heme-regulated inhibitor (HRI). Phosphorylated eIF-2 was freed from HRI by phosphocellulose column chromatography. Analysis by isoelectric focusing showed 100% phosphorylation of the 38,000-dalton subunit of eIF-2. Both...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Das, A, Ralston, R O, Grace, M, Roy, R, Ghosh-Dastidar, P, Das, H K, Yaghmai, B, Palmieri, S, Gupta, N K
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1979
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/291924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.10.5076
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