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Protein synthesis in rabbit reticulocytes: characteristics of the protein factor RF that reverses inhibition of protein synthesis in heme-deficient reticulocyte lysates.

During heme deficiency in reticulocyte lysates, the heme-regulated translational inhibitor of protein synthesis (HRI) is activated and shuts off protein synthesis. In partial reactions, HRI phosphorylates the Mr 38,000 subunit (alpha subunit) of eukaryotic initiation factor 2 (eIF-2), which forms a...

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Detalhes bibliográficos
Main Authors: Grace, M, Ralston, R O, Banerjee, A C, Gupta, N K
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC347158/
https://ncbi.nlm.nih.gov/pubmed/6959132
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