Protein synthesis in rabbit reticulocytes: a study of the mechanism of action of the protein factor RF that reverses protein synthesis inhibition in heme-deficient reticulocyte lysates.

A eukaryotic initiation factor 2 (eIF-2)-ancillary protein factor Co-eIF-2 promotes displacement of GDP from eIF-2 X GDP and facilitates ternary complex (Met-tRNAf X eIF-2 X GTP) formation in the presence of Mg2+. Heme-regulated protein synthesis inhibitor, HRI, phosphorylates the alpha-subunit of e...

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Bibliographic Details
Main Authors: Grace, M, Bagchi, M, Ahmad, F, Yeager, T, Olson, C, Chakravarty, I, Nasrin, N, Banerjee, A, Gupta, N K
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC391707/
https://ncbi.nlm.nih.gov/pubmed/6591195
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