The Effect of Shiga Toxin on Weibel-Palade Bodies in Primary Human Endothelial Cells

BACKGROUND/AIMS: Diarrhea-associated hemolytic uremic syndrome is associated with the presence of Shiga toxin (Stx1, Stx2 and several variants) in the circulation. The aim of this study is to examine the possible triggering effect of Stx1 on the exocytosis of Weibel-Palade bodies (WPbs). METHODS: Cu...

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Hauptverfasser: Geelen, Joyce, van den Biggelaar, Maartje, Linssen, Peter, van der Velden, Thea, Mertens, Koen, Monnens, Leo
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2014
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130816/
https://ncbi.nlm.nih.gov/pubmed/25177338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000363299
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