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Congenital heart disease linked to maternal autoimmunity against cardiac myosin

Structural congenital heart disease (CHD) has not previously been linked to autoimmunity. In our study, we developed an autoimmune model of structural CHD that resembles hypoplastic left heart syndrome (HLHS), a life-threatening CHD primarily affecting the left ventricle. Because cardiac myosin (CM)...

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Autors principals: Cole, Charles R., Yutzey, Katherine E., Brar, Anoop K., Goessling, Lisa S., VanVickle-Chavez, Sarah J., Cunningham, Madeleine W., Eghtesady, Pirooz
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130707/
https://ncbi.nlm.nih.gov/pubmed/24670798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301264
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