Congenital heart disease linked to maternal autoimmunity against cardiac myosin

Structural congenital heart disease (CHD) has not previously been linked to autoimmunity. In our study, we developed an autoimmune model of structural CHD that resembles hypoplastic left heart syndrome (HLHS), a life-threatening CHD primarily affecting the left ventricle. Because cardiac myosin (CM)...

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Main Authors: Cole, Charles R., Yutzey, Katherine E., Brar, Anoop K., Goessling, Lisa S., VanVickle-Chavez, Sarah J., Cunningham, Madeleine W., Eghtesady, Pirooz
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130707/
https://ncbi.nlm.nih.gov/pubmed/24670798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301264
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