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Congenital heart disease linked to maternal autoimmunity against cardiac myosin

Structural congenital heart disease (CHD) has not previously been linked to autoimmunity. In our study, we developed an autoimmune model of structural CHD that resembles hypoplastic left heart syndrome (HLHS), a life-threatening CHD primarily affecting the left ventricle. Because cardiac myosin (CM)...

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Detalhes bibliográficos
Main Authors: Cole, Charles R., Yutzey, Katherine E., Brar, Anoop K., Goessling, Lisa S., VanVickle-Chavez, Sarah J., Cunningham, Madeleine W., Eghtesady, Pirooz
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130707/
https://ncbi.nlm.nih.gov/pubmed/24670798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301264
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