Coxsackievirus B3 Infection Early in Pregnancy Induces Congenital Heart Defects Through Suppression of Fetal Cardiomyocyte Proliferation

BACKGROUND: Coxsackievirus B (CVB) is the most common cause of viral myocarditis. It targets cardiomyocytes through coxsackie and adenovirus receptor, which is highly expressed in the fetal heart. We hypothesized CVB3 can precipitate congenital heart defects when fetal infection occurs during critic...

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Bibliografiset tiedot
Julkaisussa:J Am Heart Assoc
Päätekijät: Sharma, Vipul, Goessling, Lisa S., Brar, Anoop K., Joshi, Chetanchandra S., Mysorekar, Indira U., Eghtesady, Pirooz
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2021
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955305/
https://ncbi.nlm.nih.gov/pubmed/33440998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.017995
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