Coxsackievirus B3 Infection Early in Pregnancy Induces Congenital Heart Defects Through Suppression of Fetal Cardiomyocyte Proliferation

BACKGROUND: Coxsackievirus B (CVB) is the most common cause of viral myocarditis. It targets cardiomyocytes through coxsackie and adenovirus receptor, which is highly expressed in the fetal heart. We hypothesized CVB3 can precipitate congenital heart defects when fetal infection occurs during critic...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Sharma, Vipul, Goessling, Lisa S., Brar, Anoop K., Joshi, Chetanchandra S., Mysorekar, Indira U., Eghtesady, Pirooz
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955305/
https://ncbi.nlm.nih.gov/pubmed/33440998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.017995
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