Coxsackievirus B3 Infection Early in Pregnancy Induces Congenital Heart Defects Through Suppression of Fetal Cardiomyocyte Proliferation

BACKGROUND: Coxsackievirus B (CVB) is the most common cause of viral myocarditis. It targets cardiomyocytes through coxsackie and adenovirus receptor, which is highly expressed in the fetal heart. We hypothesized CVB3 can precipitate congenital heart defects when fetal infection occurs during critic...

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Bibliografische gegevens
Gepubliceerd in:J Am Heart Assoc
Hoofdauteurs: Sharma, Vipul, Goessling, Lisa S., Brar, Anoop K., Joshi, Chetanchandra S., Mysorekar, Indira U., Eghtesady, Pirooz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955305/
https://ncbi.nlm.nih.gov/pubmed/33440998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.017995
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