Characterization of virus-like particles in GARDASIL® by cryo transmission electron microscopy

Cryo-transmission electron microscopy (cryoTEM) is a powerful characterization method for assessing the structural properties of biopharmaceutical nanoparticles, including Virus Like Particle-based vaccines. We demonstrate the method using the Human Papilloma Virus (HPV) VLPs in GARDASIL®. CryoTEM,...

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Autors principals: Zhao, Qinjian, Potter, Clinton S, Carragher, Bridget, Lander, Gabriel, Sworen, Jaime, Towne, Victoria, Abraham, Dicky, Duncan, Paul, Washabaugh, Michael W, Sitrin, Robert D
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
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Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130261/
https://ncbi.nlm.nih.gov/pubmed/24299977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.27316
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