Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

BACKGROUND: Human papillomavirus (HPV) vaccines based on major capsid protein L1 are licensed in over 100 countries to prevent HPV infections. The yeast-derived recombinant quadrivalent HPV L1 vaccine, GARDASIL(R), has played an important role in reducing cancer and genital warts since its introduct...

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Main Authors: Zhao, Qinjian, Modis, Yorgo, High, Katrina, Towne, Victoria, Meng, Yuan, Wang, Yang, Alexandroff, Jaime, Brown, Martha, Carragher, Bridget, Potter, Clinton S, Abraham, Dicky, Wohlpart, Dave, Kosinski, Mike, Washabaugh, Mike W, Sitrin, Robert D
格式: Artigo
語言:Inglês
出版: BioMed Central 2012
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308208/
https://ncbi.nlm.nih.gov/pubmed/22356831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-52
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