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Immunoproteasome in animal models of Duchenne muscular dystrophy

Increased proteasome activity has been implicated in the atrophy and deterioration associated with dystrophic muscles of Duchenne muscular dystrophy (DMD). While proteasome inhibitors show promise in the attenuation of muscle degeneration, proteasome inhibition-induced toxicity was a major drawback...

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Autors principals: Chen, Chiao-nan (Joyce), Graber, Ted G., Bratten, Wendy M., Ferrington, Deborah A., Thompson, LaDora V.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130177/
https://ncbi.nlm.nih.gov/pubmed/24934129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-014-9385-x
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