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Structural Mass Spectrometry of the αβ-Tubulin Dimer Supports a Revised Model of Microtubule Assembly()

The molecular basis of microtubule lattice instability derives from the hydrolysis of GTP to GDP in the lattice-bound state of αβ-tubulin. While this has been appreciated for many years, there is ongoing debate over the molecular basis of this instability and the possible role of altered nucleotide...

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Bibliografiska uppgifter
Huvudupphovsmän: Bennett, Melissa J., Chik, John. K., Slysz, Gordon W., Luchko, Tyler, Tuszynski, Jack, Sackett, Dan L., Schriemer, David C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129956/
https://ncbi.nlm.nih.gov/pubmed/19388626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900200q
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