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A Unique Mode of Microtubule Stabilization Induced by Peloruside A
Microtubules are a significant therapeutic target for the treatment of cancer, where suppression of microtubule dynamicity by drugs such as paclitaxel forms the basis of clinical efficacy. Peloruside A, a macrolide isolated from New Zealand marine sponge Mycale hentscheli, is a microtubule stabilizi...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441936/ https://ncbi.nlm.nih.gov/pubmed/18405918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.03.026 |
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