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Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen

Naturally occurring fragments of the abundant semen proteins prostatic acid phosphatase (PAP) and semenogelins form amyloid fibrils in vitro. These fibrils boost HIV infection and may play a key role in the spread of the AIDS pandemic. However, the presence of amyloid fibrils in semen remained to be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Usmani, Shariq M., Zirafi, Onofrio, Müller, Janis, Sandi-Monroy, Nathallie, Yadav, Jay K., Meier, Christoph, Weil, Tanja, Roan, Nadia R., Greene, Warner C., Walther, Paul, Nilsson, K. Peter R., Hammarström, Per, Wetzel, Ronald, Pilcher, Christopher D., Gagsteiger, Friedrich, Fändrich, Marcus, Kirchhoff, Frank, Münch, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129123/
https://ncbi.nlm.nih.gov/pubmed/24691351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4508
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