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Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells.

Human melanoma cells can process the MAGE-1 gene product and present the processed nonapeptide EADPTGHSY on their major histocompatibility complex class I molecules, HLA-A1, as a determinant for cytolytic T lymphocytes (CTLs). Considering that autologous antigen presenting cells (APCs) pulsed with t...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Mukherji, B, Chakraborty, N G, Yamasaki, S, Okino, T, Yamase, H, Sporn, J R, Kurtzman, S K, Ergin, M T, Ozols, J, Meehan, J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41290/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644541/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.8078
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