TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

High levels of transforming growth factor-β (TGFβ) correlate with poor prognosis for patients with prostate cancer and other cancers. TGFβ is a multifunctional cytokine and crucial regulator of cell fate, such as epithelial to mesenchymal transition (EMT), which is implicated in cancer invasion and...

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Hlavní autoři: Thakur, Noopur, Gudey, Shyam Kumar, Marcusson, Anders, Fu, Jing Yi, Bergh, Anders, Heldin, Carl-Henrik, Landström, Marene
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128885/
https://ncbi.nlm.nih.gov/pubmed/25483191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29339
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