Genetically engineered Newcastle disease virus expressing interleukin-2 and TNF-related apoptosis-inducing ligand for cancer therapy

Recombinant Newcastle disease virus (rNDV) have shown oncolytic therapeutic efficacy in preclinical studies and are currently in clinical trials. In this study, we have evaluated the possibility to enhance the cancer therapeutic potential of NDV by means of inserting both interleukin-2 (IL-2) and tu...

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Main Authors: Bai, Fu-Liang, Yu, Yin-Hang, Tian, Hui, Ren, Gui-Ping, Wang, Hui, Zhou, Bing, Han, Xiao-Hui, Yu, Qing-Zhong, Li, De-Shan
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128865/
https://ncbi.nlm.nih.gov/pubmed/24971746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29686
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