Genetically engineered Newcastle disease virus expressing interleukin-2 and TNF-related apoptosis-inducing ligand for cancer therapy

Recombinant Newcastle disease virus (rNDV) have shown oncolytic therapeutic efficacy in preclinical studies and are currently in clinical trials. In this study, we have evaluated the possibility to enhance the cancer therapeutic potential of NDV by means of inserting both interleukin-2 (IL-2) and tu...

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Bibliografische gegevens
Hoofdauteurs: Bai, Fu-Liang, Yu, Yin-Hang, Tian, Hui, Ren, Gui-Ping, Wang, Hui, Zhou, Bing, Han, Xiao-Hui, Yu, Qing-Zhong, Li, De-Shan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2014
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128865/
https://ncbi.nlm.nih.gov/pubmed/24971746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29686
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