Dendritic Cell-Mediated, DNA-Based Vaccination against Hepatitis C Induces the Multi-Epitope-Specific Response of Humanized, HLA Transgenic Mice

Hepatitis C virus (HCV) is the etiologic agent of chronic liver disease, hepatitis C. Spontaneous resolution of viral infection is associated with vigorous HLA class I- and class II-restricted T cell responses to multiple viral epitopes. Unfortunately, only 20% of patients clear infection spontaneou...

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Main Authors: Mishra, Sasmita, Lavelle, Bianca J., Desrosiers, Joe, Ardito, Matt T., Terry, Frances, Martin, William D., De Groot, Anne S., Gregory, Stephen H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128787/
https://ncbi.nlm.nih.gov/pubmed/25111185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104606
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