An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice

Immunoinformatics tools were used to predict human leukocyte antigen (HLA) class II-restricted T cell epitopes within the envelope glycoproteins and nucleocapsid proteins of Ebola virus (EBOV) and Sudan virus (SUDV) and the structural proteins of Venezuelan equine encephalitis virus (VEEV). Selected...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Bounds, Callie E., Terry, Frances E., Moise, Leonard, Hannaman, Drew, Martin, William D., De Groot, Anne S., Suschak, John J., Dupuy, Lesley C., Schmaljohn, Connie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718811/
https://ncbi.nlm.nih.gov/pubmed/28575582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1329788
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