CFIm25 links Alternative Polyadenylation to Glioblastoma Tumor Suppression

The global shortening of mRNAs through alternative polyadenylation (APA) that occurs during enhanced cellular proliferation represents an important, yet poorly understood mechanism of regulated gene expression(1,2). The 3′UTR truncation of growth promoting mRNA transcripts that relieves intrinsic mi...

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Huvudupphovsmän: Masamha, Chioniso P., Xia, Zheng, Yang, Jingxuan, Albrecht, Todd R., Li, Min, Shyu, Ann-Bin, Li, Wei, Wagner, Eric J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128630/
https://ncbi.nlm.nih.gov/pubmed/24814343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13261
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