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Clonal Progression during the T Cell-Dependent B Cell Antibody Response Depends on the Immunoglobulin D(H) Gene Segment Repertoire
The diversity of the third complementarity determining region of the IgH chain is constrained by natural selection of immunoglobulin diversity (D(H)) sequence. To test the functional significance of this constraint in the context of thymus-dependent (TD) immune responses, we immunized BALB/c mice wi...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4128299/ https://ncbi.nlm.nih.gov/pubmed/25157256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00385 |
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