Evidence of a Role for the Novel Zinc-finger Transcription Factor ZKSCAN3 in Modulating Cyclin D2 Expression in Multiple Myeloma

Dysregulation of cyclin D2 contributes to the pathogenesis of multiple myeloma, and can occur through translocations that activate MAF/MAFB or MMSET/FGFR3. However, cyclin D2 induction can also be seen in the absence of such translocations, such as in patients with hyperdiploid disease, through unkn...

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Detalhes bibliográficos
Main Authors: Yang, Lin, Wang, Hua, Kornblau, Steven M., Graber, David A., Zhang, Nianxian, Matthews, Jairo A., Wang, Michael, Weber, Donna M., Thomas, Sheeba K., Shah, Jatin J., Zhang, Li, Lu, Gary, Zhao, Ming, Mudasani, Ramya, Yoo, Suk-Young, Baggerly, Keith A., Orlowski, Robert Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128235/
https://ncbi.nlm.nih.gov/pubmed/21057542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.515
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