The N-terminal domain of the androgen receptor drives its nuclear localization in castration-resistant prostate cancer cells

Androgen-independent nuclear localization is required for androgen receptor (AR) transactivation in castration-resistant prostate cancer (CRPC) and should be a key step leading to castration resistance. However, mechanism(s) leading to androgen-independent AR nuclear localization are poorly understo...

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Autors principals: Dar, Javid A., Masoodi, Khalid Z., Eisermann, Kurtis, Isharwal, Sudhir, Ai, Junkui, Pascal, Laura E., Nelson, Joel B., Wang, Zhou
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127361/
https://ncbi.nlm.nih.gov/pubmed/24662325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2014.03.004
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