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Autoreactivity in HIV-1 broadly neutralizing antibodies: implications for their function & induction by vaccination

PURPOSE OF REVIEW: This review discusses progress in understanding the impact of immune tolerance on inducing broadly neutralizing antibodies (BnAbs), and how such knowledge can be incorporated into novel immunization approaches. RECENT FINDINGS: Over 120 BnAbs have now been isolated, all of which b...

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Detalhes bibliográficos
Main Authors: Verkoczy, Laurent, Diaz, Marilyn
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127310/
https://ncbi.nlm.nih.gov/pubmed/24714565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0000000000000049
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