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Essential role of Elmo1 in Dock2-dependent lymphocyte migration
Elmo1 and Elmo2 are highly homologous cytoplasmic adapter proteins that interact with Dock family guanine nucleotide exchange factors to promote activation of the small GTPase Rac. In T lymphocytes, Dock2 is essential for CCR7- and CXCR4-dependent Rac activation and chemotaxis, but the role of Elmo...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127066/ https://ncbi.nlm.nih.gov/pubmed/24821968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303348 |
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