Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47

Under normal physiologic conditions, cellular homeostasis is partly regulated by balancing pro- and anti-phagocytic signals. CD47 is highly expressed on several human cancers including acute myeloid leukemia, non-Hodgkin lymphoma, and bladder cancer, allowing cancer cells to evade phagocytosis by th...

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Detalhes bibliográficos
Main Authors: Chao, Mark P., Jaiswal, Siddhartha, Weissman-Tsukamoto, Rachel, Alizadeh, Ash A., Gentles, Andrew J., Volkmer, Jens, Weiskopf, Kipp, Willingham, Stephen B., Raveh, Tal, Park, Christopher Y., Majeti, Ravindra, Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126904/
https://ncbi.nlm.nih.gov/pubmed/21178137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3001375
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